Research designs utilizing large- scale data collection across diverse populations, or big data, represent a major step towards
personalizing clinical applications of music. To advance these designs, we aim to establish feasibility of patients participating
in music cognition research via a flexible -length, gamified musical memory task in a clinic waiting- room setting and linking
to large-scale health data via electronic health records (EHR). This approach harnesses the intrinsic motivation and validity
of gamified (and musical) tasks (Honing, 2021) to engage a diverse adult participant population representative of the clinical
population already present at the medical center. We implemented the That’s My Song game, which involves recognizing short
fragments of music (15s) and maintaining an auditory image of recognized music during short periods of silence (4s). The game
uses musical fragments from the Billboard Hot 100 charts for the decades of interest first selected by the participants. Self-report
musicality questions are interspersed between the scored game rounds. Our pilot phase of the study enrolled N=187 participants
in Vanderbilt University Medical Center Otolaryngology outpatient clinics; 90.9% have fidelity of procedure scores indicating
usable data. Of the usable data, participants are mean age ± SD = 55.22 ±16.2 years (range 18.7- 86.24), 47.06% male, 51.76%
female, 1.18% other gender identity. Of participants who completed one full round (N = 90), the mean game score was 2.50 ±
3.48 as compared to scores of 3.27 ± 3.50 for previous versions of the game in non-clinical populations. We will map ICD codes
from 219 participant EHR data to PheCodes in preparation for a phenome-wide association study (pheWAS) to explore the connections
between health phenotypes and game scores. This pilot is groundwork for future studies linking individual differences in musicality
traits (e.g., music memory tasks or self-reported music achievement) to risk and resilience for health traits (e.g., age-related
cognitive impairment).